KCR may refer to:

• K. Chengalaraya Reddy, first Chief Minister of the former Indian state of Mysore
• K. Chandrashekar Rao, the first and former Chief Minister of the Indian state of Telangana
• Kansas City Royals, a Major League Baseball team
• Karachi Circular Railway, the proposed metro rail system of Karachi, Pakistan
• Kienning Colloquial Romanized, a romanization system adopted by Western missionaries to compile the Kienning dialect (modern day Jian'ou City) of the Northern Min language in the Fujian Province of China
• KCR, a landmark crossroads in Dublin, Ireland
• KCR CRO, Contract Research Organization
• KCR (SDSU), a student-run radio station at San Diego State University in San Diego, California, United States
• Kowloon–Canton Railway (disambiguation)