Langbahn Team – Weltmeisterschaft

KCNG1

KCNG1
Identifiers
AliasesKCNG1, K13, KCNG, KV6.1, kH2, potassium voltage-gated channel modifier subfamily G member 1
External IDsOMIM: 603788; MGI: 3616086; HomoloGene: 20515; GeneCards: KCNG1; OMA:KCNG1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002237
NM_172318

NM_001081134
NM_001379458

RefSeq (protein)

NP_002228

NP_001074603
NP_001366387

Location (UCSC)Chr 20: 51 – 51.02 MbChr 2: 168.1 – 168.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.[5][6][7]

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.[7]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000026559Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074575Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Su K, Kyaw H, Fan P, Zeng Z, Shell BK, Carter KC, Li Y (Feb 1998). "Isolation, characterization, and mapping of two human potassium channels". Biochem Biophys Res Commun. 241 (3): 675–81. doi:10.1006/bbrc.1997.7830. PMID 9434767.
  6. ^ Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.
  7. ^ a b "Entrez Gene: KCNG1 potassium voltage-gated channel, subfamily G, member 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.