Jose Diaz may refer to:

• José Díaz (politician) (1895–1942), Spanish politician
• José Enrique Díaz Chávez (born 1932), Uruguayan politician, see List of ministers of the interior
• José Ramón Díaz (born 1973), Puerto Rican Senator
• José Félix Díaz (born 1980), Republican politician from Florida

• José Díaz (bobsleigh) (1907–1988), Mexican bobsledder
• José Díaz (footballer, born 1938), Argentine footballer
• José Antonio Díaz (fencer) (born 1938), Cuban fencer
• José Narciso Díaz (born 1950), Cuban Olympic fencer
• José Enrique Díaz (born 1953), Spanish football manager
• José Guadalupe Díaz (born 1954), Mexican football manager and former player
• José Díaz Pablo (born 1955), Spanish footballer
• José Díaz (weightlifter) (born 1959), Panamanian weightlifter
• José Díaz (rugby union) (born 1963), Spanish rugby union player
• Manolo Díaz (born 1968), Spanish football manager born José Manuel Díaz
• José Luis Díaz (footballer, born 1974), Argentinian footballer
• José Ignacio Díaz (born 1979), Spanish racewalker
• Joselo Díaz (born 1980), Major League Baseball player
• Jumbo Díaz (born 1984), Dominican baseball player
• José Daniel Díaz (born 1989), Venezuelan freestyle wrestler
• José Manuel Díaz (cyclist) (born 1995), Spanish cyclist
• José Díaz (weightlifter) (born 1959), Panamanian weightlifter

• José and Francisco Díaz (1777–1797), Puerto Rican soldiers who defended Puerto Rico against a British invasion in 1797
• José María Díaz (1813–1888), Spanish journalist and playwright
• José E. Díaz (1833–1867), Paraguayan general
• José Gallardo Díaz (1919–1942), victim of the Los Angeles Sleepy Lagoon murder
• José Pedro Díaz (1921–2006), Uruguayan essayist, educator and writer
• José Díaz-Balart (born 1960), American journalist
• Jose "Pepi" Diaz, American attorney and The Apprentice contestant
• Joey Diaz (born 1963), Cuban American stand-up comedian