John Reynolds may refer to:

• John Reynolds (actor) (born 1991), American actor and writer
• John Reynolds (musician), record producer, the first husband of singer Sinéad O'Connor
• John Reynolds (writer) (1588–1655), English merchant and writer
• John Hamilton Reynolds (1794–1852), English poet, satirist, critic, and playwright
• John Lawrence Reynolds (born 1939), Canadian author
• Jonathan Reynolds (writer) (1942–2021), American actor and writer

• John Reynolds (Roundhead) (1625–1657), soldier in the English Civil War
• John Reynolds (Royal Navy officer) (1713–1788), British naval officer and governor of the Province of Georgia
• John F. Reynolds (1820–1863), American army officer active in the US Civil War
• John Williams Reynolds (1817–1874), British cavalry officer and researcher into organic chemistry

• John Reynolds (1670–1699), Irish Member of Parliament
• John Reynolds (Canadian politician) (born 1942), Canadian politician from British Columbia
• John Reynolds (Dublin politician) (1797–1868)
• John Reynolds (Illinois politician) (1788–1865), American politician, governor of Illinois
• John Reynolds (Indiana politician) (1814–1890), American politician from Indiana
• John A. Reynolds (1820–1889), American politician from Pennsylvania
• John F. Reynolds (politician) (1852–1934), American politician from Wisconsin
• John Hazard Reynolds (1819–1875), American politician from New York
• John Merriman Reynolds (1848–1933), American politician from Pennsylvania
• John W. Reynolds Sr. (1876–1958), American politician from Wisconsin
• John W. Reynolds Jr. (1921–2002), American politician, governor of Wisconsin
• Jonathan Reynolds (born 1980), British politician, Labour Co-operative MP for Stalybridge and Hyde

• John Reynolds (agriculturist) (1703–1779), English farmer and agricultural innovator
• John Reynolds (astronomer) (1874–1949), British astronomer
• John Reynolds (ecologist) (born 1959), Canadian ecologist
• John Reynolds (physicist) (1923–2000), American physicist
• John C. Reynolds (1935–2013), American computer scientist
• John Russell Reynolds (1828–1896), British neurologist
• John Reynolds (neuroscientist), American neuroscientist

• John Reynolds (motorcyclist) (born 1963), British motorcycle racer
• John J. Reynolds (1889–1987), American track and field athlete

• John Reynolds (priest), English Anglican priest
• J.F. Reynolds (John F. Reynolds), American architect
• John Henry Reynolds (educator) (1842–1927), British champion of technical education
• John N. Reynolds, banker
• John W. Reynolds (Oregon attorney) (1875–1942), American attorney and educator

• Reynolds-Morris House, in Philadelphia, Pennsylvania, built in 1786–87 by John and William Reynolds
• Jon A. Reynolds (1937–2022), United States Air Force officer
• Jack Reynolds (disambiguation)
• Gen. John F. Reynolds School, in Philadelphia, Pennsylvania, United States
• John Rainolds or Reynolds (1549–1607), English academic and churchman
• John Reynolds Gardiner (1944–2006), American author and engineer
• John Reynold, MP for Bath, England