John Butler may refer to:

• John "Picayune" Butler (died 1864), American banjo performer; may have been used by a number of performers
• John Butler (artist) (1890–1976), American artist
• John Butler (author) (born 1937), British author and YouTuber
• John Butler (born 1954), member of Diesel Park West
• John Butler (director) (born 1972), Irish screenwriter, director and novelist
• John Butler (musician) (born 1975), Australian musician
  • John Butler Trio, his jam band
  • John Butler (album), its 1998 album
• John Butler (Doctors), a fictional character from Doctors

• John Butler (Irish Confederate), officer of the Irish Confederate Army of the 1640s
• John Butler (Ranger) (1728–1796), American-born military officer
• John Butler (general) (died 1786), brigadier general of militia in North Carolina during the American Revolutionary War
• John A. Butler (1910–1945), U.S. Marine Corps officer and Navy Cross recipient
• John Fitzhardinge Paul Butler (1888–1916), English soldier and Victoria Cross recipient
• John Clarence Butler (1921–1942), U.S. naval aviator
  • USS John C. Butler, a ship named in his honor
• John G. Butler (inventor), 19th century officer in the U.S. Army Ordnance Corps who developed better shot for rifled cannon

• John Butler of Clonamicklon (died 1330), youngest son of Edmund Butler, Earl of Carrick
• John Butler, 6th Earl of Ormond (died 1476)
• John Butler of Kilcash (died 1570), third son of James Butler, 9th Earl of Ormond
• John Butler, 1st Earl of Gowran (1643–1677), seventh son of James Butler, 1st Duke of Ormonde
• John Butler, 12th Baron Dunboyne (1731–1800), Irish clergyman and aristocrat, Roman Catholic Bishop of Cork
• John Butler, 17th Earl of Ormonde (1740–1795), Irish peer and Member of Parliament
• John Butler, 2nd Marquess of Ormonde (1808–1854), Irish politician and peer
• John Butler, 15th Earl of Ormonde (before 1744–1766)

• John Butler (MP for Kent) (c. 1370–c. 1420)
• John Butler (died 1423), MP for London
• John Butler (died 1572 or 1573) (1503/04–1572/73), MP for Warwick
• John Butler (died 1576) (1511/14–1576), MP for Hertfordshire
• John Butler (died 1613), MP for Maldon
• John Butler (Nova Scotia politician) (died 1791)
• John Washington Butler (1875–1952), U.S. Representative for Tennessee
• John Cornelius Butler (1887–1953), U.S. Congressman from New York
• John Butler (Irish politician) (1891–1968), Irish Labour party politician from Waterford; member of the 4th Dáil
• John Marshall Butler (1897–1978), American politician in Maryland
• John D. Butler (1915–2010), American Republican politician and mayor of San Diego
• John Edward Butler (1916–1999), member of the Legislative Assembly of Alberta from 1975 to 1979
• John E. Butler, American politician, lawyer, and newspaper editor from Maine

• John Butler (Jesuit) (1727–1786), Jesuit priest
• John Butler (priest) (died 1682), Canon of Windsor
• John Butler (bishop) (1717–1802), bishop of Oxford
• John Gare Butler (1781–1841), clergyman of New Zealand
• John Jay Butler (1814–1891), ordained minister and professor of systematic theology
• John George Butler (1826–1909), Lutheran clergyman; Chaplain of the U.S. Senate and House of Representatives
• John Joseph Butler (1883–1966), Catholic priest

• John Butler (American football coach) (born 1973), American football assistant coach since the 1990s
• John Butler (American football executive) (1946–2003), general manager in the National Football League
• John Butler (defensive back) (born 1965), National Football League player with the San Francisco 49ers
• Johnny Butler (running back) (1918–1963), National Football League player from 1942 to 1945

• John Butler (footballer, born 1937) (1937–2010), English footballer
• John Butler (footballer, born 1962), English footballer
• John Butler (footballer, born 1969), Scottish footballer

• John Butler (cricketer) (1863–1945), English cricketer
• John Butler (athlete) (1871–1959), British Olympic athlete
• John Butler (baseball) (1879–1950), catcher in Major League Baseball from 1901 to 1907
• John Butler Jr. (born 2002), American basketball player
• Johnny Butler (1893–1967), baseball player
• John Butler (rugby league) (born 1949), English rugby league footballer
• John Butler (jockey), rider in the 1847 Grand National steeplechase

• John O. Butler, American dentist and periodontist
• John M. Butler (scientist), expert on forensic DNA typing
• John Alfred Valentine Butler, English physical chemist
• John Dixon Butler, British architect
• John Butler (actor) (1884–1967), actor in The Yellow Cab Man
• John S. Butler, founding member of the American Psychiatric Association

• Butler dynasty
• Jack Butler (disambiguation)
• John Boteler (disambiguation)
• John Butler Smith (1838–1914), American manufacturer and politician
• Jonathan Butler (born 1961), South African singer-songwriter