James Boyce may refer to:

• James Petigru Boyce (1827–1888), American theologian
• James F. Boyce (1868–1935), American chemist
• James Boyce (Louisiana politician) (1922–1990), American businessman and chairman of the Louisiana Republican Party
• Jim Boyce (born 1944), former Vice-President of FIFA
• Jim Boyce (rugby union) (born 1941), Australian rugby union player
• Jimmy Boyce (1947–1994), British politician
• Jim Boyce (tennis) (1951-), Canadian tennis player
• James Boyce (author), Tasmanian academic and anti-gambling advocate