High five is a friendly gesture in which one individual slaps another's hand.

High five (and variants such as Hi5, Hi-5, and Hi-Five) may also refer to:

• Hi-5 (Australian group), an Australian children's musical group
• Hi-5 (Greek band), a Greek all-girl pop group
• Hi-5 (South African band), a South African boy band
• Hi-Five, an R&B quintet from Waco, Texas
  • Hi-Five (album)
• The Hi-Fives, a rock and roll band from San Francisco, California
• Hi-Five (Israeli band), a 1990s Israeli boy band
• Jim Lowe and the High Fives, 1950s band
• High Five (album), by Teen Top
• "Hi-Five" (song), a song by Superfly
• "High Five" (Yuma Nakayama song), 2014
• "High 5 (Rock the Catskills)", a song by Beck from Odelay
• Maori High Five, a Maori group from New Zealand

• Hi-5 (Australian TV series), the television series starring the Australian group
  • Hi-5 (American TV series), American version of the Australian series
  • Hi-5 Philippines, Philippines version of the Australian series
  • Hi-5 (British TV series), British version of the Australian series
  • Hi-5 (Indonesian TV series), 2017, Indonesian version of the Australian series
• "High Five" (Power Rangers), an episode of Mighty Morphin Power Rangers

• High Five (Columbus), a business district in Columbus, Ohio
• High Five Interchange, a Dallas freeway interchange
• High 5s Project, an international collaboration promoting patient safety activities
• hi5, a social networking website
• Highfive (company), an American video conferencing company
• High 5 Tickets to the Arts, New York non-profit for students
• HIV (slang reference)
• High Five cells, a strain of insect cells
• High Five (novel), a novel by Janet Evanovich
• High Fives Gang, 1890s outlaws
• HiFive, a series of single board computers.
• High Five is another name for Cinch (card game)
• 'Hi Five', a 1950s compact, containing 'Misty Amber' face powder, by Max Factor

• Give me five