Grodner is a surname. Notable people with the surname include:

• Allison Grodner, American director, producer and writer
• Annetta Grodner, Ukrainian Jewish singer and actress, the first prima donna in Yiddish theater
• Israel Grodner (1848–1887), one of the founding performers in Yiddish theater
• Nahum Grodner (1811–1879), preacher and philanthropist