Gatti is an Italian surname. Notable people with the surname include:

• Alessandra Mirka Gatti, Italian Eurobeat singer
• Annibale Gatti, Italian 19th-century fresco painter
• Armand Gatti (1924–2017), French playwright
• Arturo Gatti, Italian-Canadian professional boxer
• Attilio Gatti, Italian explorer of Africa
• Bernardino Gatti, Italian painter of the Renaissance
• Bruno Gatti (1941–2012), Swiss footballer
• Carlo Gatti, Swiss entrepreneur in the Victorian era
• Carmine Biagio Gatti (born 1988), Italian professional football player
• Claudio Gatti, Italian investigative journalist based in New York City
• Daniele Gatti, Italian conductor
• Darío Javier Franco Gatti (born 1969), Argentine football manager and a former international footballer
• Eduardo Gatti (born 1949), Chilean singer-songwriter
• Elena Gatti Caporaso (1918–1999), Italian socialist politician and feminist
• Emilio Gatti (1922–2016), Italian engineer and professor of nuclear electronics at the Politecnico of Milan
• Enrico Gatti (born 1955), Italian violinist, known for playing Baroque music
• Enrique Gatti, German musician of the English and German indie rock band Art Brut
• Fabio Gatti, Italian footballer
• Fabrizio Gatti (born 1966), Italian investigative journalist and author
• Federico Gatti (born 1998), Italian professional footballer
• Fortunato Gatti (early 17th century) was an Italian painter active near Parma and Modena
• Franco Gatti (1942–2022), the founder of the Italian group Ricchi e Poveri
• Gabriele Gatti, Sammarinese politician
• Gabriella Gatti (1908–2003), Italian operatic soprano
• Gervasio Gatti (c. 1550–c. 1631), Italian late-Renaissance, active in Parma, Piacenza, and Cremona
• Giacomo Gatti (died 1817), Italian painter of the late-Baroque, active mainly in his native Mantua
• Girolamo Gatti (1682–1726), Italian painter, active mainly in Bologna.
• Giulio Gatti-Casazza, Italian opera manager
• Guido Carlo Gatti (born 1938), Italian former basketball player
• Héctor Gustavo Gatti (born 1972), former Argentine footballer
• Hugo Gatti, former Argentine professional football goalkeeper
• Isabelle Laure Gatti de Gamond (1839–1905), Belgian educationalist, feminist, and politician
• Joe Gatti (born 1967), Canadian former middleweight boxer
• John Maria Emilio Gatti, Sir (1872–1929), Anglo-Swiss theatre manager, restaurateur and businessman
• Lou Gatti (1915-1977), Australian rules footballer
• Lucas Cassius Gatti (born 1978), retired Argentine football midfielder
• Luigi Gatti (composer) (1740–1817), Venetian classical composer
• Luigi Gatti (businessman) (1875–1912), restaurateur
• Luigi Gatti (weightlifter), Italian weightlifter
• Luigi Gatti (politician) (1913–1945), Italian politician
• Luigi Gatti (nuncio) (born 1946), Vatican diplomat
• Marcello Gatti (1924–2013), Italian cinematographer
• María Ester Gatti de Islas (1918–2010), Uruguayan teacher and human rights activist
• Natalia Gatti (born 1982), Argentine female football forward
• Mauro Gatti (born 1937), a retired Italian professional football player and coach
• Nando Gatti (1927-date of death unknown), former South African international lawn bowler
• Oliviero Gatti (1579–1648), Italian painter and engraver
• Pierluigi Gatti (born 1938), Italian athlete
• Rafael Savério Gatti (born 1984), Brazilian football goalkeeper
• Riccardo Gatti (born 1997), Italian football player
• Federico Gatti (born 1998), Italian football player
• Roberta Gatti, Italian economist
• Roberto Gatti (born 1954), retired Italian football defender and later manager
• Saturnino Gatti (1463–1518), Italian painter and sculptor
• Simon Gatti, Canadian soccer player
• Stanlee Gatti (born 1955), American event designer
• Theobaldo di Gatti (c.1650-1727), Florentine composer and musician