File:180-TALEffectors TALEN.png
Size of this preview: 800 × 341 pixels. Other resolutions: 320 × 137 pixels | 640 × 273 pixels | 1,655 × 706 pixels.
Original file (1,655 × 706 pixels, file size: 782 KB, MIME type: image/png)
Summary
| Description | English: Space-filling drawing of an engineered TAL effector/nuclease bound to double-helical DNA. TALE proteins contain a series of alpha-helical hairpin domains, each of which binds an individual DNA base, so that the protein recognizes a long, very specific DNA sequence. This engineered construct attaches the specific FOK1 nuclease to one end of the TALE protein, and when two copies bind as a dimer the nuclease cleaves both strands of the DNA. Drawn by David Goodsell from PDB files 1FOK (nuclease/DNA) and 3UGM (TALE/DNA). |
| Date | |
| Source | RCSB PDB Molecule of the Month |
| Author | David Goodsell |
Licensing
This file is licensed under the Creative Commons Attribution 3.0 Unported license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 14:35, 24 December 2014 | | 1,655 × 706 (782 KB) | Dcrjsr | User created page with UploadWizard |
File usage
The following 3 pages use this file:
Global file usage
The following other wikis use this file:
- Usage on th.wikipedia.org
