El Refugio ("The Refuge") may refer to:

• El Refugio, Ahuachapán, a municipality in the Ahuachapán department of El Salvador
• El Refugio, Baja California, a city in the Tijuana municipality of Baja California, Mexico
• El Refugio, Jalisco, a town in the Tizapan El Alto municipality of Jalisco, Mexico
• El Refugio, Texas, a census-designated place (CDP) in Starr County, Texas, United States

• El refugio (film), 2021 internationally co-produced film
• El refugio (TV series), Mexican telenovela
• El Refugio (de los Sueños), Argentine television series

• Refugio (disambiguation)