ESV is an abbreviation of the English Standard Version, a translation of the Bible in contemporary English.

ESV may also refer to:

• Emergency shutdown valve
• Employer-supported volunteering, a form of corporate volunteering
• End-systolic volume
• ESV, a brand of Cadillac Escalade
• Exact sequence variant, also called an amplicon sequence variant
• Experimental safety vehicle
• M1132 engineer squad vehicle
• Engineering Standards and Validation, a term specific to some quality assurance roles and processes in engineering