Dost is a surname. People with the surname include:

• Abdul Rahim Muslim Dost (born 1960), Afghan journalist and jeweller
• Andrew Dost (born 1983), American musician
• Bas Dost (born 1989), Dutch football player
• Bernd Dost (1939–2015), German journalist, filmmaker, writer and publisher
• Erol Dost (born 1999), Bulgarian football player
• Jan Dost (born 1965), Syrian Kurdish poet
• Jeanne Dost, American economist
• Kader Dost (born 2000), Turkish race walker
• Marcel Dost (born 1969), Dutch decathlete
• Sultan Mohammad Dost (born 1932), Afghan wrestler