Devil May Care may refer to:

• Devil May Care, an album by Bob Dorough, 1956
  • "Devil May Care", the title song, covered by Jamie Cullum on Pointless Nostalgic, 2002
• Devil May Care (album), by Teri Thornton, 1961
• Devil May Care, an album by Claire Martin, 1993
• "The Devil May Care (Mom & Dad Don't)", a song by the Brian Jonestown Massacre from Give It Back!, 1997
• Devil May Care (EP) or the title song, by Susperia, 2005
• The Devil May Care, an album by 67 Special, 2007
• Devil May Care, an EP by Iron Steel, 2008

• Devil-May-Care, a 1929 film musical starring Ramón Novarro
• Devil May Care (Peters novel), a 1977 novel by Elizabeth Peters
• Devil May Care (Faulks novel), a 2008 James Bond novel by Sebastian Faulks
• Devil May Care (horse) (2007–2011), an American Thoroughbred racehorse
• Devil May Care (TV series), a 2021 American adult animated comedy series

• Devil May Cry, a video game series