Deion is a given name. Notable people with the name include:

• Deion Barnes (born 1993), American football player
• Deion Belue (born 1991), American football player
• Deion Branch (born 1979), American football player
• Deion Harris (born 1995), American football player
• Deion Jones (born 1994), American football player
• Deion Jumah (born 1989), English boxer
• Deion Mikesell (born 1987), American rugby union player
• Deion Sanders (born 1967), American football coach, former football and baseball player
• Deion Turman (born 1992), American basketball player

• Deioneus, or Deion, several figures in Greek mythology
• Deon, given name
• d'Eon, a surname
• Dion (disambiguation), includes a list of people with given name Dion
• Dione (disambiguation), includes a list of people with given name Dione