Defacement or disfigurement may refer to:

• Defacement (vandalism), the vandalism of physical objects, like buildings, books, paintings and statues
• Website defacement, an attack on a website that changes the visual appearance of the site
• Defacement (flag), a term used in heraldry and vexillology
• Disfigurement, the state of having one's appearance deeply and persistently harmed medically
• Disfigured, a 2015 extended play by Rag'n'Bone Man
• Disfigure (now HYLO), a music artist signed to NoCopyrightSounds