David Griffin may refer to:

• David Griffin (actor) (born 1943), English actor
• David Griffin (American football) (born 1991), American football offensive lineman
• David Griffin (athlete) (1905–1944), Canadian Olympic athlete
• David Griffin (basketball) (born 1973), American basketball executive
• David Griffin (hurler) (born 1997), Irish hurler
• David Griffin (politician) (1915–2004), Australian politician
• David Griffin (swimmer) (born 1967), Australian swimmer
• David Ray Griffin (1939–2022), American philosopher and theologian
• Dave Lee Travis (born David Patrick Griffin; 1945), English radio presenter and DJ