Charles Belgique Hollande de La Trémoïlle, 5th Duke of Thouars (May 1655 – 1 June 1709), 5th Duke of Thouars, was a French nobleman.

He was the second child and eldest son of Henri Charles de La Trémoille (son and heir of Henri de La Trémoille, 3rd Duke of Thouars and his wife Marie de La Tour d'Auvergne) and his wife Princess Emilie of Hesse-Kassel (daughter of William V, Landgrave of Hesse-Kassel and his wife Countess Amalie Elisabeth of Hanau-Münzenberg).

Brought up a Calvinist, in 1668 his father had converted to Catholicism and then forcibly converted his children as well. His mother and eldest sister fled to the Netherlands.

On 3 April 1675 he married Madeleine de Créquy (1655-1707), daughter and heiress of Charles de Créquy and his wife Anne Armande de Saint Gelais. The couple had two children:

1. Marie Armande de La Trémoille (1677-1717) who married Emmanuel Théodose de La Tour d'Auvergne, Duke of Bouillon, The Prince of Turenne (later Reigning Duke of Bouillon from 1721); They had Seven children.
2. Charles Louis Bretagne de La Trémoille who succeeded him as The 6th Duke of Thouars as well as other titles in 1709; He married Marie Madeleine Motier and they had one child.