Protein-coding gene in the species Homo sapiens
Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene .[ 5] [ 6]
Interactions CBX8 has been shown to interact with RING1 [ 7] MLLT1 .[ 8]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000141570 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025578 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Bardos JI, Saurin AJ, Tissot C, Duprez E, Freemont PS (Oct 2000). "HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties" . J Biol Chem . 275 (37): 28785– 92. doi :10.1074/jbc.M001835200 PMID 10825164 . ^ "Entrez Gene: CBX8 chromobox homolog 8 (Pc class homolog, Drosophila)" .^ Bárdos JI, Saurin A J, Tissot C, Duprez E, Freemont P S (Sep 2000). "HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties" . J. Biol. Chem . 275 (37): 28785– 92. doi :10.1074/jbc.M001835200 ISSN 0021-9258 . PMID 10825164 . ^ García-Cuéllar MP, Zilles O, Schreiner S A, Birke M, Winkler T H, Slany R K (Jan 2001). "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3" . Oncogene . 20 (4): 411– 9. doi :10.1038/sj.onc.1204108 ISSN 0950-9232 . PMID 11313972 .
External links
Further reading
García-Cuéllar MP, Zilles O, Schreiner SA, et al. (2001). "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3" . Oncogene . 20 (4): 411– 9. doi :10.1038/sj.onc.1204108 PMID 11313972 . Hemenway CS, de Erkenez AC, Gould GC (2001). "The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias". Oncogene . 20 (29): 3798– 805. doi :10.1038/sj.onc.1204478 . PMID 11439343 . S2CID 25138105 . Levine SS, Weiss A, Erdjument-Bromage H, et al. (2002). "The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans" . Mol. Cell. Biol . 22 (17): 6070– 8. doi :10.1128/MCB.22.17.6070-6078.2002 . PMC 134016 PMID 12167701 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40– 5. doi :10.1038/ng1285 PMID 14702039 . Obuse C, Yang H, Nozaki N, et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase" . Genes Cells . 9 (2): 105– 20. doi :10.1111/j.1365-2443.2004.00705.x PMID 15009096 . S2CID 21813024 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome" . Cell . 122 (6): 957– 68. doi :10.1016/j.cell.2005.08.029 hdl :11858/00-001M-0000-0010-8592-0 PMID 16169070 . Dietrich N, Bracken AP, Trinh E, et al. (2007). "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus" . EMBO J . 26 (6): 1637– 48. doi :10.1038/sj.emboj.7601632 . PMC 1829390 PMID 17332741 .
