Butts is a surname. Notable people with the name include:

• Alan Butts (born 1940), British Olympic wrestler
• Alfred Butts (disambiguation), multiple people
• Anthony Butts (born 1969), American poet
• Arthur C. Butts (1848–1913), American lawyer, judge, and politician
• Augustus De Butts (1770–1853), officer in the Royal Engineers
• Calvin O. Butts (1949–2022), Pastor of the Abyssinian Baptist Church in the City of New York
• Cassandra Butts (1965–2016), American lawyer
• Cassius F. Butts (born 1971), American business executive
• Charles Butts (disambiguation), multiple people
• Colin Butts (1959–2018), English writer
• Clyde Butts (1957–2023), West Indies cricketer
• George Butts (1838–1902), American soldier, Medal of Honor recipient
• Gerald Butts (born 1971), Canadian political adviser
• Gerard Butts (born 1966), Australian rules footballer
• Evelyn Thomas Butts (1924–1993), American civil rights activist
• Henry Butts, Vice-Chancellor of the University of Cambridge (1629–1631)
• Henry De Butts, United States Army officer, acting Adjutant General and acting Inspector General (1792–1793)
• Ingrid Butts (born 1963), American Olympic cross-country skier
• Isaac Butts (born 1989), American basketball player
• James Butts (born 1950), American triple jumper
• James T. Butts Jr. (born 1953), American politician, mayor of Inglewood, California (since 2011)
• Jimmy Butts (1917–1998), American jazz double-bassist
• John Butts (disambiguation), multiple people
• Lisa Butts (born 1982), American rugby union player
• Mr. Butts, fictional character in Garry Trudeau's Doonesbury
• Marie Butts (1870–1953), French educator, translator, and children's book author; first General Secretary of the International Bureau of Education (1926–1953)
• Marion Butts (born 1966), American football running back
• Mary Butts (1890–1937), British modernist writer
• Niya Butts (born 1978), American women's college basketball coach
• Pee Wee Butts (Thomas Lee Butts; 1919–1972), American baseball player
• Peggy Butts (1924–2004), Canadian Senator
• Ray Butts (Joseph Raymond Butts; 1919–2003), American inventor and engineer
• Robert Butts (disambiguation), multiple people
• Samuel Butts (1777–1814), American militia officer in the Creek War
• Seymore Butts (born 1964), American pornographic film director, producer, and actor
• Skyler Butts (born 1993), Hong Kong tennis player
• Tasha Butts (born 1982), American women's basketball player and coach
• Thomas Butts (1757-1845), British senior civil servant, and patron to the artist and poet William Blake
• Vibert Butts, Guyanese soccer player
• Vernon Butts, American serial killer and accomplice of William Bonin
• W. E. Butts (Walter E. Butts; 1944–2013), American poet
• Wally Butts (1905–1973), University of Georgia football head coach and athletic director
• Wanda Butts, American swimming activist
• William Butts (c. 1486 – 1545), member of King Henry VIII of England's court

• Charles W. Buttz (1837–1913), American politician
• Buts, surname
• Butz, surname
• Butt (surname)