Robert or Bob Casey may refer to:

• Robert E. Casey (1909–1982), Pennsylvania Treasurer, 1977–1981
• Robert R. Casey (1915–1986), House of Representatives member from Texas
• Robert F. Casey (1921–2006), Illinois House of Representatives member
• Robert K. Casey (1931–2015), Florida House of Representatives member
• Bob Casey Sr. (1932–2000), 42nd Governor of Pennsylvania, 1987–1995
• Bob Casey Jr. (born 1960), son of Bob Casey Sr., Senator from Pennsylvania 2007-2025
• Rob Casey, automotive designer in 2004 United States House of Representatives elections for Michigan 10

• Bob Casey (third baseman) (1859–1939), Canadian who played for Detroit Wolverines
• Bob Casey (baseball announcer) (1925–2005), American announcer for Minnesota Twins
• Bob Casey (rugby union) (born 1978), Irish lock for Leinster and London Irish

• Robert J. Casey (1890–1962), American journalist of World War I and II
• Bob Casey (musician) (1909–1986), American jazz double-bassist
• Robert Gerald Casey (born 1967), American Catholic Auxiliary Bishop of Chicago