A biphasic disease is a disease which has two distinct phases or components. In clinically biphasic diseases, the phases are generally chronologically separated. In histopathologically biphasic tumors (also called biplastic tumors), there is neoplastic tissue which contains two different cellular elements.[1][2]
After approximately 4 days, patients develop flu-like illness with fever, nonproductive cough, and myalgias lasting approximately 4 days
Without timely treatment, a second fulminant phase follows, characterized by hypotension and dyspnea. This phase may progress to death within 24 hours of its onset.[6]
^Tavassoli F, Devilee P, eds. (2003). World Health Organization Classification of Tumours: Pathology & Genetics: Tumours of the breast and female genital organs. Lyon: IARC Press. ISBN 978-92-832-2412-9.[page needed]