Apamea or Apameia (Ancient Greek: Απάμεια) is the name of several Hellenistic cities in western Asia, after Apama, the Sogdian wife of Seleucus I Nicator, several of which are also former bishoprics and Catholic titular see.

Places called Apamea include:

• Apamea (Euphrates), in Osroene, opposite Zeugma on the Euphrates, now flooded by the Birecik Dam
• Apamea (Phrygia) or Apamea Cibotus, formerly Kibotos, commercial center of Phrygia, near Celaenae, now at Dinar, Afyonkarahisar Province; former bishopric and now a Latin Catholic titular bishopric
• Apamea Myrlea or Apamea in Bithynia, formerly Myrlea and Brylleion, in Bithynia, on the Sea of Marmara; currently near Mudanya, Bursa Province; former archdiocese, Latin Catholic titular archbishopric

• Apamea (Babylonia), on the Tigris near the Euphrates, precise location unknown
• Apamea (Sittacene), on the Tigris, precise location unknown

• Apamea (Media), in Media, near Laodicea (Nahavand, Iran), precise location unknown
• Apamea Ragiana, south of the Caspian Gates, in Parthia (later Media)

• Apamea, Syria, on the Orontes River, northwest of Hama, Syria, a former Roman provincial capital and Metropolitan Archbishopric, now
  • Latin Catholic titular Metropolitan archbishopric
  • Melkite Catholic titular Metropolitan archbishopric
  • Syriac Catholic Catholic titular Metropolitan archbishopric
  • Greek Orthodox titular bishopric
  • Maronite Catholic titular bishopric

• Treaty of Apamea
• Apama (disambiguation)