Anthony, Antony, or Tony Walker may refer to:

• Anthony Walker (rower) (born 1939), Australian Olympic rower
• Anthony Walker (rugby league) (born 1991), rugby league player
• Tony Walker (outfielder) (born 1959), American baseball player
• Tony Walker (pitcher), American baseball player
• Anthony Walker Jr. (born 1995), American football player
• Tony Walker (American football) (born 1968), American football player

• Anthony Walker (artist) (1726–1765), English printmaker
• Anthony Guy Walker (born 1957), American criminal and serial killer
• Anthony Walker (politician) (born 1965), American politician
• Antony Walker (1934–2023), British general
• Murder of Anthony Walker, high-profile British murder in 2005
• Antony Walker (conductor), Australian-born conductor of mostly opera
• Tony Walker (born 1956), British participant in the Up (film series) documentaries

• John Anthony Walker (1937–2014), US Navy officer convicted of spying for the Soviet Union