Americans in Ireland comprise Irish citizens and residents who have full or partial American descent or ancestral background. These individuals often use the term 'American-Irish', in order to differentiate from the Irish-American cultural group.

Those with American-Irish dual citizenship represent 16.8% of all Irish people with dual nationality.^[1] As of 2016, there are 10,519 Americans in Ireland without any Irish citizenship.

Voter registration drives occurred in the run-up to the 2020 American Presidential Election. Democrats Abroad maintains a notable political base in the country. Cultural events, such as the Fourth of July and Thanksgiving are celebrated by the resident American population, as well as other affiliated groups.^[2] Several towns with large American populations host fireworks displays, while the American Chamber of Commerce hosts an annual Thanksgiving dinner, which is attended by the Taoiseach.^[3][4] Black Friday (Aoine Mhór na Siopadóireachta - literally Big Friday of Shopping) has become widely observed in Ireland, however, largely facilitated by physical retailers competing with internet sale promotions, though remains largely detached from its Thanksgiving roots.^{[citation needed]}

• Erskine Hamilton Childers – 4th President of Ireland
• Éamon de Valera – 3rd President of Ireland
• Frank McCourt – Irish-American writer
• Marsha Hunt – African American singer and novelist
• Matt Doyle – Irish professional tour tennis player
• Constantine Fitzgibbon – Historian and novelist
• Chryss Goulandris – American businesswoman
• Lennie McMillian – Irish professional basketball player
• Tom Molineaux – Bare-knuckle boxer
• Charles Stewart Parnell – Founder and leader of the Irish Parliamentary Party
• Darren Randolph – Irish football goalkeeper
• Saoirse Ronan – American-born Irish actress
• Kevin Shields – American-born Irish musician
• Des Bishop – American-raised Irish comedian
• Ronan O'Gara – American born rugby player
• Dana Rosemary Scallon – singer and politician
• Katherine Zappone – American-born Irish Senator and academic

• Irish American
• Ireland–United States relations