Alfred Johnson may refer to:

• Alfred "Centennial" Johnson (1846–1927), Danish-born fisherman and sailor
• Alfred Wilkinson Johnson (1876–1963), U.S. Navy officer
• Alfred F. Johnson (1884–1972), English academic librarian and expert in typography
• Alfred I. Johnson (1898–1977), Minnesota politician
• Al Johnson (musician) (1948–2013), American R&B singer, writer, arranger and producer
• Alfred E. Johnson, anthropologist and archaeologist at the University of Kansas
• Alfred C. Johnson, American molecular biologist

• Alfred Johnson Brooks (1890–1967), Canadian parliamentarian
• Al Johnson (disambiguation)