AFRC can be an initialism for:

• Advanced Frame Rate Converter, used for frame rate control
• Agricultural and Food Research Council, British farming and horticulture organisation
• Air Force Reserve Command, major command of the United States Air Force
• Arkansas Forest Resource Center, University of Arkansas at Monticello, United States
• Armed Forces Revolutionary Council, rebel group in Sierra Leone
• Armed Forces Revolutionary Council, Ghana, ruled Ghana for 4 months in 1979
• Armed Forces Recreation Center, resorts run by the United States Armed Forces for members of the military and their families
• Neil A. Armstrong Flight Research Center, a NASA center on Edwards Air Force Base in California, United States

• Australian Family Relationships Clearinghouse Issues, aka AFRC Issues
• American Flame Research Committee, component of the International Flame Research Foundation