The 2000 United States Senate election in West Virginia took place on November 7, 2000. Incumbent Democratic U.S. Senator Robert Byrd won re-election to an eighth term. He won every county and congressional district in the state with at least 60% of the vote. This was despite the fact that Republican presidential candidate George W. Bush won the state on the same ballot.
Byrd would go on to become the longest serving U.S. senator in the history of the United States Senate at the end of this term, surpassing Strom Thurmond. He would additionally be reelected one further time.