Singles
2000 Grand Prix de Tennis de Lyon
Final
Champion	Arnaud Clément
Runner-up	Patrick Rafter
Score	7–6(7–2), 7–6(7–5)
Events
Singles Doubles
← 1999 · Grand Prix de Tennis de Lyon · 2001 →

Nicolás Lapentti was the defending champion, but did not participate this year.

Arnaud Clément won the tournament, beating Patrick Rafter 7–6^(7–2), 7–6^(7–5) in the final.

	Semifinals							Final
	8	Patrick Rafter	6	6
		Hicham Arazi	3	4
								8	Patrick Rafter	62	65
									Arnaud Clément	77	77
		Arnaud Clément	6
	2	Andre Agassi	3r

	First round							Second round							Quarterfinals							Semifinals
	1	G Kuerten	77	6
		A Pavel	65	4				1	G Kuerten	7	77
		A Costa	66	6	3			WC	M Llodra	5	64
	WC	M Llodra	78	1	6										1	G Kuerten	3	4
		Y El Aynaoui	77	77											8	P Rafter	6	6
		A Ilie	65	64					Y El Aynaoui	64	2
		G Gaudio	4	6	4			8	P Rafter	77	6
	8	P Rafter	6	4	6																	8	P Rafter	6	6
	3	T Enqvist	4	6	6																		H Arazi	3	4
		S Grosjean	6	3	4			3	T Enqvist	6	63	6
	Q	J-F Bachelot	5	77	6			Q	J-F Bachelot	3	77	3
		K Alami	7	61	4										3	T Enqvist	78	66	4
	WC	J Boutter	3	6	4											H Arazi	66	78	6
		H Arazi	6	3	6				H Arazi	6	3	7
		W Ferreira	3	712	3			6	M Philippoussis	3	6	5
	6	M Philippoussis	6	610	6

	First round							Second round							Quarterfinals							Semifinals
	5	F Squillari	6	4	6
		F Santoro	2	6	1			5	F Squillari	6	2	3
		A Clément	7	4	6				A Clément	3	6	6
	Q	T Guardiola	5	6	1											A Clément	6	3	77
		M Puerta	77	6											Q	R Sluiter	3	6	65
		M Chang	64	4					M Puerta	6	4	1r
	Q	R Sluiter	6	77				Q	R Sluiter	4	6	4
	4	À Corretja	4	62																			A Clément	6
	7	C Pioline	4	65																		2	A Agassi	3r
		K Kučera	6	77					K Kučera	3	6	6
		R Federer	6	77					R Federer	6	2	1
		N Escudé	3	63												K Kučera	1	5
		T Haas	6	6											2	A Agassi	6	7
	WC	A Di Pasquale	3	3					T Haas	2	3
	Q	S Sargsian	77	1	4			2	A Agassi	6	6
	2	A Agassi	63	6	6

• Main Draw
• Qualifying Draw