The 1978 Ole Miss Rebels football team represented the University of Mississippi (Ole Miss) during the 1978 NCAA Division I-A football season as a member of the Southeastern Conference (SEC). The team was led by head coach Steve Sloan, in his first year, and they played their home games at Hemingway Stadium in Oxford, Mississippi, and Mississippi Memorial Stadium in Jackson, Mississippi. Some of the outstanding players on the team of that year were Bobby Garner, Leon Perry, Reginald Woullard, Roy Coleman, Freddie Williams, etc. They finished the season with a record of five wins and six losses (5–6, 2–4 SEC).

Date	Opponent	Site	TV	Result	Attendance	Source
September 9	Memphis State*	Mississippi Veterans Memorial Stadium Jackson, MS (rivalry)		W 14–7	47,535	[1]
September 23	at No. 17 Missouri*	Faurot Field Columbia, MO		L 14–45	60,287	[2]
September 30	Southern Miss*	Mississippi Veterans Memorial Stadium Jackson, MS		W 16–13	42,756	[3]
October 7	at Georgia	Sanford Stadium Athens, GA		L 3–42	58,800	[4]
October 14	Kentucky	Hemingway Stadium Oxford, MS		L 17–24	38,290	[5]
October 21	at South Carolina*	Williams–Brice Stadium Columbia, SC		L 17–18	50,226	[6]
October 28	at Vanderbilt	Dudley Field Nashville, TN (rivalry)		W 35–10	25,043	[7]
November 4	at No. 12 LSU	Tiger Stadium Baton Rouge, LA (rivalry)	ABC	L 8–30	73,120	[8]
November 11	Tulane*	Hemingway Stadium Oxford, MS (rivalry)		W 13–3	28,500	[9]
November 18	at Tennessee	Neyland Stadium Knoxville, TN (rivalry)		L 17–41	83,210	[10]
November 25	vs. Mississippi State	Mississippi Veterans Memorial Stadium Jackson, MS (Egg Bowl)		W 27–7	47,012	[11]
*Non-conference game Homecoming Rankings from AP Poll released prior to the game

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