Events from the year 1641 in art.

• Claude Lorrain completes a series of twelve etchings of land- and seascapes.
• Gerard Dou and Diego Velázquez are painting.

• Claude Lorrain – The Embarkation of St. Ursula
• Guercino
  • The Flagellation of Christ
  • The Suicide of Cato
• Willem Claesz. Heda – The Blackcurrant Pie
• Luis de Morales – Madonna della Purità
• Le Nain brothers – Venus at Vulcan's Forge
• Nicolas Poussin – Time Rescuing Truth from the Assaults of Discord and Envy
• Rembrandt
  • The Girl in a Picture Frame^[1]
  • The Scholar at the Lectern
  • The Concord of the State
  • Portrait of Agatha Bas
  • Portrait of Nicolaes van Bambeeck
  • Portrait of the Mennonite preacher Cornelius Claesz Anslo and his wife Aeltje Gerritsdr Schouten
  • Saskia as Flora
  • The Windmill (etching)
• Andrea Sacchi – Marcantonio Pasqualini Crowned by Apollo
• Sebastian Stoskopff – Great Vanity
• Sir Anthony van Dyck – Self-portrait
• Johannes Cornelisz Verspronck – Girl in a Blue Dress

• May – Johann Weikhard von Valvasor, Carniolan nobleman, scientist, writer, draughtsman, and polymath (died 1693)
• May 17 – Pierre Monier, French painter (died 1703)
• September 8 – Jacobus Storck, Dutch Golden Age painter (died 1700)
• September 11 – Gerard de Lairesse, Dutch Golden Age painter and art theorist (died 1711)
• September 22 – Titus van Rijn, son and model of Rembrandt (died 1668)
• date unknown
  • Johann Franz Ermels, German painter and engraver (died 1693)
  • Juan Conchillos Falco, Spanish painter (died 1711)
  • Thomas Heeremans, Dutch Golden Age painter (died 1694)
  • Pieter Peutemans, Dutch Golden Age painter (died 1698)
  • Pasquale Rossi, Italian painter (died 1718)
  • Antoinette Bouzonnet-Stella, French engraver (died 1676)
  • Tao Chi, Chinese landscape painter (died 1720)
  • Herman Verelst, Dutch Golden Age portrait and still life painter (died 1690)
  • Jan Pietersz Zomer, Dutch engraver, copyist, and art collector (died 1724)

• January 11 – Juan de Jáuregui, Spanish poet and painter (born 1583)
• April 16 – Domenichino (Domenico Zampieri), Italian Baroque painter (born 1581)
• June 27 – Michiel Jansz van Mierevelt, Dutch painter, born at Delft (born 1567)
• November – Andrés López Polanco, Spanish Baroque portrait painter (born unknown)
• December 9 – Sir Anthony van Dyck, Flemish Baroque painter who became the leading court painter in England (born 1599)
• date unknown
  • Juan Bautista de Espinosa, Spanish still life painter (born 1590)
  • Léonard Gaultier, French engraver (born 1561)
  • Lazzaro Tavarone, Genoese painter (born 1556)
  • Adam van Noort, Flemish painter and draughtsman (born 1561/1562)
  • Artus Wolffort, Flemish painter (born 1581)
• probable – Ottavio Viviani, Italian painter of quadratura (born 1579)