VUK or Vuk may refer to:

• Vuk (name), South Slavic given name
  • Vuk, Ban of Bosnia (fl. 14th c.), a member of the Kotromanić dynasty
  • Vuk Karadžić (1787–1864), Serbian language reformer and folklorist, often referred to simply as Vuk
• Vuk (film), an animated Hungarian movie from 1981
• Vuk (novel), a 1965 novel by Istvan Fekete
• Vuk, a D'Bari character in the 2019 film Dark Phoenix
• Vuk (computer), 1980s Yugoslavian computer prototype
• VUK-T (glider), often called VUK, a 1970s high-performance Yugoslavian sailplane
• Vuk., taxonomic author abbreviation for Ljudevit Vukotinović (1813–1893), Croatian naturalist
• Volume Unique Key, in the AACS encryption system from the 2000s
• Value Up Kit
• Vertical up-kicker, a pinball part