Rajagopalachari is a given name used amongst the Iyengar community of Tamil Nadu.

Notable people with the name include:

• C. Rajagopalachari (1878–1972), Indian statesman, writer, lawyer, and independence activist
• Parthasarathi Rajagopalachari (1927–2014), Indian yoga master
• Perungavur Rajagopalachari (1862–1927), Indian civil servant and administrator