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Philip S. Low (American)

Not to be confused with Philip S. Low (Canadian).
Philip Stewart Low
Born1947
West Lafayette, Indiana, United States
CitizenshipUnited States
EducationPh.D., UCSD (1975)
B.S., BYU (1971)
FatherPhilip F. Low
AwardsGeorge & Christine Sosnovsky Award For Cancer Research (American Chemical Society)
Scientific career
FieldsBiopharmacology
ThesisMolecular mechanisms of enzyme adaptation to temperature and pressure (1975)
Websitewww.chem.purdue.edu/people/profile/plow

Philip Stewart Low is an American scientist and the Ralph C. Corley Distinguished Professor of Chemistry at Purdue University. Low is a prolific researcher whose work has supported numerous drug discoveries and he is credited as one of the developers of Pluvicto. He cofounded the biotechnology company Endocyte, which was later acquired by Novartis, as well as the biopharmaceutical company Novosteo, which was purchased by Cortexyme.

Low is a recipient of the American Chemical Society's George & Christine Sosnovsky Award For Cancer Research. He is the son of agronomist Philip F. Low.

Early life and education

Philip Low's father, Philip F. Low, was a pioneering argonomist noted as one of the first American scientists invited to lecture in the People's Republic of China (PRC) following the establishment of diplomatic relations between the United States and the PRC.[1] Born in Carmangay, Alberta, Canada, he relocated to Utah with his family while in high school and later attended Brigham Young University.[1][2][3] The elder Low was granted U.S. citizenship in 1940 and served as a meteorologist in the U.S. Army Air Corps during World War II.[1] He went on to earn a doctorate in chemistry from Iowa State University before beginning a long academic career at Purdue University.[1]

Philip S. Low attended West Lafayette Junior-Senior High School in West Lafayette, Indiana.[4] According to Low, he struggled in his high school science courses but — encouraged by his father — went on to study chemistry at Brigham Young University on a basketball scholarship, where he earned a Bachelor of Science degree.[5][2][6] He was a Mormon missionary to West Germany and subsequently completed a Ph.D. at the University of California, San Diego.[5][6]

Career

In 1976, Low joined the faculty of Purdue University where his father was, at the time, also teaching.[6] He has remained at Purdue since then and, as of 2025, is the Ralph C. Corley Distinguished Professor of Chemistry.[4]

Low's scientific work has resulted in numerous drug discoveries, he is the author or coauthor of more than 350 scholarly articles, and he has been listed on more than 600 patents.[7][5] In 2014, Purdue University constructed the Drug Discovery Building on its West Lafayette, Indiana campus in part to accommodate Low's expansive research.[8][9] Low, along with Timothy Ratliff and Tom Gardner, is credited with the development of the prostate cancer drug Pluvicto, which was granted breakthrough status by the Food and Drug Administration in 2021.[10]

In the late 1990s, Low cofounded, with Christopher Leamon, biotechnology company Endocyte where he served as chief science officer.[8] The company was purchased by Novartis in 2018 in a $2.1 billion sale.[8] He later founded Novosteo, a clinical-stage biopharmaceutical company, which was acquired by Cortexyme in 2022.[11]

In 2015, Low received the American Chemical Society's George & Christine Sosnovsky Award For Cancer Research, and the American Association for Cancer Research's Award for Outstanding Achievement in Chemistry in Cancer Research. He is an elected fellow of the National Academy of Inventors.[5][12]

Personal life

Low is married with five children and 18 grandchildren.[11][13]

Low is a member of the Church of Jesus Christ of Latter Day Saints.[6] He has said that "science supports and, in fact, confirms" his belief in Mormonism.[6]

See also

References

  1. ^ a b c d Gardner, W.R. (2000). Biographical Memoirs. National Academy of Sciences. pp. 109–115. Retrieved February 8, 2025.
  2. ^ a b This Is Purdue – Full Interview with Professor Philip Low (YouTube video). Purdue University. January 20, 2022. Retrieved February 8, 2025.
  3. ^ "Alumni Achievers". Y Magazine. Brigham Young University. Winter 2014. Retrieved February 8, 2025.
  4. ^ a b "Philip Low". wlsef.org. West Lafayette Junior-Senior High School. Retrieved February 8, 2025.
  5. ^ a b c d Goldberg-Gist, Arlene (February 2, 2015). "George & Christine Sosnovsky Award For Cancer Research". Chemical & Engineering News. Retrieved February 8, 2025.
  6. ^ a b c d e Sheffield, Sheridan R. (May 30, 1992). "His work is strength to testimony". Church News. Church of Jesus Christ of Latter Day Saints. Retrieved February 8, 2025.
  7. ^ "Purdue researcher awarded $1.3 million for malaria drug trials in Southeast Asia and Africa". WLFI-TV. September 18, 2023. Retrieved February 8, 2025.
  8. ^ a b c Bangert, Dave (October 18, 2018). "Purdue startup Endocyte sold in $2.1B deal with pharmaceutical giant Novartis". Journal & Courier. Retrieved February 8, 2025.
  9. ^ "Drug Discovery Building". purdue.edu. Purdue University. Retrieved February 8, 2025.
  10. ^ "Member Feature: Purdue Center for Cancer Research". bigtencrc.org. Big Ten Cancer Research Consortium. Retrieved February 8, 2025.
  11. ^ a b Ellison, Jillian (March 1, 2019). "Purdue affiliated startup receives award for bone repair acceleration". Journal & Courier. Retrieved February 8, 2025.
  12. ^ "Purdue professor wins national cancer research award". purdue.edu. Purdue University. Retrieved February 8, 2025.
  13. ^ "50th Anniversary Gala: Join Virtually". byu.edu. Brigham Young University. Retrieved February 8, 2025.

Further reading

Quelle: Https://en.wikipedia.org/wiki/Philip_S._Low_(American)