Panni may refer to:

• Plural of Latin pannus

• Panni, Apulia, village in the province of Foggia in southeast Italy
• Panni (Pashtun tribe), in Afghanistan and Pakistan

• Antonio Maria Panni (1730-1790), Italian painter and art historian
• Daud Khan Panni (died 1715), Mughal commander
• Humayun Khan Panni (died 2006), Bangladesh politician
• Morshed Ali Khan Panni, Bangladesh politician
• Muhammad Bayazeed Khan Panni, Bangladesh politician, doctor, writer, and social reformer
• Nicoletta Panni (1933–2017), Italian lyric soprano
• Raissa Khan-Panni, also known as Raissa (born 1971), English singer-songwriter
• Wazed Ali Khan Panni (1871–1936), Bengali Zamidar, politician, and philanthropist