Margaret of Denmark may refer to:

• Margaret Fredkulla (1080s–1130), wife of king Niels of Denmark
• Margarethe of Bohemia (1186–1212), a.k.a. Queen Dagmar, first wife of Valdemar II of Denmark
• Margaret Sambiria (1230–1282) of Pomerelia, wife of king Christopher I of Denmark
• Martha of Denmark (1277–1341), wife of King Birger Magnusson of Sweden
• Margaret I of Scandinavia (1353–1412), wife of Haakon VI of Norway, daughter of Valdemar IV of Denmark, mother of Olaf II of Denmark, also ruled Scandinavia as de facto queen regnant
• Margaret of Denmark, Queen of Scotland (1456–1486), queen-consort of James III of Scotland
• Princess Margaret of Denmark (1895–1992), wife of Prince René of Bourbon-Parma, daughter of Prince Valdemar of Denmark and mother of Queen Anne of Romania
• Princess Margaretha of Sweden (1899–1977), Princess of Denmark through her marriage to Prince Axel
• Margrethe II of Denmark (born 1940), Queen-regnant of Denmark (1972-2024)