MLR may refer to:

• Mary Lynn Rajskub, actress

• MLR Institute of Technology
• Mar-Lu-Ridge Summer Camp and Education and Conference Center
• Milnrow railway station, England, UK; National Rail station code MLR

• Medical Loss Ratio, in health insurance
• Minimum lending rate
• Monotone likelihood ratio
• Money laundering regulations

• Michigan Law Review
• Minnesota Law Review
• Modern Language Review
• Modern Law Review
• Monthly Labor Review, a monthly journal published by the U.S. Bureau of Labor Statistics

• Multiple linear regression – see Linear regression
• Morse/Long-range potential
• Machine-learned ranking
• Machine Learning Runtime, a machine learning environment in Databricks (software)
• Mineralocorticoid receptor
• Mixed lymphocyte reaction
• Mesencephalic locomotor region, a region in the brainstem comprising the pedunculopontine nucleus, the cuneiform nucleus and the subcuneiform nucleus

• Major League Rugby, the professional rugby union competition of North America.
• Ministry of Land and Resources

• Metro Light Rail, the light rail in Sydney (2000–2012)
• Valley Metro Rail, the light rail network in Phoenix, Arizona
• Mid-life Refurbishment, another term for MTR MLR Train EMU

• Main Line of Resistance
• Muzzle-loading rifle
• Multiple rocket launcher
• Marine Littoral Regiment

• Major League Rugby, a professional rugby competition in the United States and Canada

• Montana Land Reliance
• Metadata for learning resources or ISO/IEC 19788, a standard to describe learning resources

• All pages with titles beginning with MLR
• All pages with titles containing MLR