James Williams may refer to:

• James Williams (musician) (1951–2004), American jazz pianist
• James J. Williams (1853–1926), English photographer
• James Dixon Williams (1877–1934), American film producer
• James D-Train Williams (born 1962), American singer-songwriter and actor
• James Lee Williams (1992–2025), British drag queen (stage name: The Vivienne)
• James K. Williams, Liberian rapper
• James Robert Williams, Canadian cartoonist

• James Williams (Revolutionary War) (1740–1780), colonel from South Carolina
• James Monroe Williams (1833–1907), American Civil War soldier
• James Howard Williams (1897–1958), British soldier and elephant expert in Burma
• James E. Williams (1930–1999), Medal of Honor in the U.S. Navy
• James A. Williams (1932–2017), U.S. Army general
• James L. Williams, U.S. Marines general
• USS James E. Williams, an American warship

• James Wray Williams (1792–1842), U.S. Representative from Maryland
• James Williams (ambassador) (1796–1869), to Ottoman Empire
• James D. Williams (1808–1880), U.S. Representative from Indiana
• James Williams (Ohio politician) (1822–1892), Republican
• James Williams (Delaware politician) (1825–1899), U.S. Representative
• James E. Williams (Atlanta mayor) (1826–1900), Atlanta mayor after the Civil War
• James E. Williams (East St. Louis mayor)
• James M. Williams (1850–1909), Ohio House and Ohio Senate
• James R. Williams (politician) (1850–1923), U.S. Representative from Illinois
• James R. Williams (lawyer) (1936–2020), candidate for lieutenant governor of Ohio
• James D. Williams (Pennsylvania politician) (1943–1985), Pennsylvania House
• James Edwin Williams (1856–1917), British trade unionist
• James Williams (labor leader), American president of painters' union
• James A. Williams Jr., American labor union leader
• James Harrison Williams, member of the Iowa House of Representatives

• James Williams (priest, died 1872) (1790–1872), Welsh Anglican cleric
• James Williams (bishop) (1825–1892), Canadian Anglican cleric and educator
• James Williams (archdeacon of Ardfert) (died 1724), Irish Anglican priest
• James Williams (archdeacon of Wrexham) (died 1953), Welsh Anglican priest
• James Kendrick Williams (born 1936), American Catholic bishop
• J. Henry Williams (1831–1889), American Episcopal priest and philanthropist

• James Williams (end) (1928–2015), Rice University
• James Williams (cornerback) (born 1967), American football cornerback
• James Williams (linebacker, born 2003) (born 2003), American football linebacker
• James Williams (wide receiver) (born 1978), American football wide receiver
• James O. Williams (born 1968), American football offensive tackle
• James Williams (linebacker, born 1968) (born 1968), American football linebacker
• James Williams (defensive lineman), American football defensive lineman
• Jamie Williams (American football) (born 1960), NFL tight end

• James Williams (Welsh footballer) (1885–1916)
• James Williams (Australian footballer) (born 1937)
• James Williams-Richardson (born 1988), Anguillan international footballer
• James Williams (Irish footballer)
• Jimmy Williams (footballer, born 1982), English footballer

• James Williams (baseball), co-owner of the Cincinnati Reds 1981–1984
• Jimmy Williams (coach) (or James Bernard Williams, 1926–2016), minor league manager
• Jimy Williams (1943–2024)

• James Williams (basketball) (born 1979), American streetball player
• Fly Williams (born 1953), American ABA and CBA player

• James Williams (British fencer) (1966–2024)
• James Williams (cricketer) (born 1973), Welsh
• James Williams (field hockey) (1878–1929), British
• James Leighman Williams (born 1985), American fencer

• James Miller Williams (1818–1890), Canadian oil businessman
• James Nelson Williams (1837–1915), New Zealand runholder, orchardist and entrepreneur
• James Leon Williams (1852–1932), American dental researcher
• James Steele Williams (1896–1957), American paleontologist
• James Arthur Williams (1930–1990), American antiques dealer
• James Wilson Williams (born 1982), American academic
• James Oladipo Williams (died 1999), Nigerian jurist and judge
• James F. Williams, American librarian, University of Colorado
• James H. Williams Jr., American mechanical engineer, MIT
• Jamie Williams, president of the Wilderness Society

• Jim Williams (disambiguation)
• William James (disambiguation)