Guardia is a surname. Notable people with the surname include:

• Gloria Guardia (1940–2019), Panamanian novelist
• Guillermo Guardia (born 1960), Costa Rican footballer
• Jaime Guardia (1933–2018), Peruvian singer
• Maribel Guardia (born 1959), Costa Rican actress
• Rómulo Guardia (born 1961), Venezuelan film producer
• Tomás Guardia Gutiérrez (1831–1882), Costa Rican politician
• Victoria Guardia Alvarado (born 1939), Costa Rican politician