David Nicholls may refer to:

• David Nicholls (cricketer) (1943–2008), Kent cricketer
• David G. Nicholls, professor of biology
• David Nicholls (footballer, born 1956), English footballer
• David Nicholls (footballer, born 1972), Scottish footballer
• David Nicholls (racehorse trainer) (1956–2017), English jockey and racehorse trainer
• David Nicholls (theologian) (1936–1996), author in the fields of political theology and Caribbean Studies
• David Nicholls (musicologist) (born 1955), English academic and composer
• David Nicholls (writer) (born 1966), English novelist and screenwriter
• David Shaw Nicholls (born 1959), Scottish architect

• David Nicholl (disambiguation)
• David Nichols (disambiguation)
• Dave Nichol (1940–2013), Canadian product marketing expert
• David Nicolle (born 1944), British historian