The Asian Television Award for Best Actress in a Leading Role is awarded annually by the Asian Television Awards.

Year	Winner and nominees	English title	Original title
15th (2010)	Rebecca Lim	The Pupil
	Yang Kuei-mei	The Grass Green Sky	芳草碧連天
	Pan Li-li	The Addict	逆子
	Jian Man-shu	Year of the Rain	那年，雨不停國
	Quan Yi Fong	The Illusionist	魔幻视界
	Jeanette Aw	Together	当我们同在一起
	Michelle Chia	Polo Boys
	Janice Koh	The Pupil
16th (2011)	Charmaine Sheh	Can't Buy Me Love	公主嫁到
	Lee Shu-chen	Fairy Suzhen	仙女不下凡
	Yu Tzu-yu	A Teacher’s Heart	我愛美金
	Zarynn Min	Gila
	Erra Fazira	Sanggul Beracun
	Miriama Smith	Stolen
17th (2012)	Rui En	Unriddle 2	最火搭档2
	Debbie Goh	The Descendant	香火
	Yeo Yann Yann	The Descendant	香火
	Sharlene San Pedro	Maalaala Mo Kaya (Episode: "T-shirt")
	Ann Kok	Show Hand	注定
	Joanne Peh	A Song to Remember	星洲之夜
18th (2013)	Jade Chou	Falling	含苞欲墜的每一天
	Lorna Tolentino	Pahiram ng Sandali
	Marian Rivera	Temptation of Wife
	Kate Tsui	Highs and Lows	雷霆掃毒
	Debbie Goh	Mining Magnate	半边天
	Fang Wen-lin	Go, Hula!	呼拉姊妹花
19th (2014)	Puteri Balqis Azizi	Balqis
	Kristal Tin	Brother's Keeper	巨輪
	Tien Hsin	A Good Wife	親愛的，我愛上別人了
	Ko Shu-chin	What Time Will You Be Home?	幾點回家
	Joan Chen	Serangoon Road
	Rui En	Sudden	骤变
20th (2015)	Zhou Xun	Red Sorghum	紅高粱
	Kristal Tin	Black Heart White Soul	忠奸人
	Ruby Lin	The Way We Were	16個夏天
	Fang Wen-lin	The Last Waltz	人生圓舞曲
	Hong Qi-yang	Messages Seen	已讀不回
	Zhao Wei	Tiger Mom	虎妈猫爸
	Felicia Chin	Love Is Love: Sunshine
	Suhaillah Salam	Dua Wajah
21st (2016)	Cheryl Yang	A Touch of Green	一把青
	Mei Fang	Laugh for 24 Hours	藥笑24小時
	Fonthip Watcharatrakul	The Sisters	เพื่อน แพง
	Ko Chia-yen	La Grande Chaumiere Violette	紫色大稻埕
	Kristal Tin	Ghost of Relativity	鬼同你OT
	Jojo Goh	The Love Machine
	Farhana M Noor	Bunga Tanjong
22nd (2017)	Kara Hui	Affairs of the Heart
	Louisa Chong	Beautiful World – Crow
	Ryoko Shinohara	Desperate for Love
	Chantel Liu	The King of Drama
	Ko Chia-yen	Welcome to the Happy Days
	Felicia Chin	2589 Days Apart
	Zoe Tay	You Can Be An Angel 2
23rd (2018)	Kim Nam-joo	Misty	미스티
	Son Ye-jin	Something in the Rain
	Ali Lee	My Ages Apart
	Herb Hsu	The Alternatives
	Joanne Tseng	Attention, Love!
	Maylada Susri	The Swan and The Dragons	หงส์เหนือมังกร
	Sonija Kwok	Below the Lion Rock – Secret
	Maja Salvador	Wildflower
	Yang Chin	Age of Rebellion