ACOM or Acom may refer to:

• Acom, a Japanese consumer loan company
• Alabama College of Osteopathic Medicine, an American medical school
• The Anglican Church of Melanesia, or the Church of the Province of Melanesia
• Association for Convention Operations Management
• Australian College of Ministries
• Agency.com, Ltd. (former NASDAQ stock ticker symbol)
• Ancestry.com, Inc. (NASDAQ stock ticker symbol)
• Acom International, a former Japanese golf tournament
• Acom-1, a model of Konica Autoreflex 35mm SLR camera