AAPC may refer to:

• AAPC (formerly the American Academy of Professional Coders), a professional organization for healthcare business professionals in the United States.
• Additive/Abradable Powder Coatings, see Abradable powder coatings
• African Auxiliary Pioneer Corps, military unit, British Empire
• All-African Peoples' Conference
• Allied Artists Pictures Corporation, the former name of a Hollywood film studio
• American Association of Pastoral Counselors, a professional association of pastoral counselors
• American Association of Political Consultants, the trade group of the political consulting profession in the United States
• American Automotive Policy Council, American automobile trade group of Ford, Chrysler, and General Motors
• Artificial antigen presenting cells
• Association des architectes paysagistes du Canada (Canadian Society of Landscape Architects)
• Australian Army Pay Corps, military unit, Australia, see Royal Australian Army Pay Corps