Protein-coding gene in the species Homo sapiens
Zinc finger and BTB domain-containing protein 7B is a protein that in humans is encoded by the ZBTB7B gene .[ 5] [ 6] [ 7] ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g. COL1A1 ; MIM 120150 ) and has a role in development.[supplied by OMIM][ 7]
See also
References
^ a b c GRCh38: Ensembl release 89: ENSG00000160685 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028042 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Widom RL, Culic I, Lee JY, Korn JH (Dec 1997). "Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression" . Gene . 198 (1–2): 407–20. doi :10.1016/S0378-1119(97)00360-0 PMID 9370309 . ^ Galera P, Musso M, Ducy P, Karsenty G (Oct 1994). "c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin" . Proc Natl Acad Sci U S A . 91 (20): 9372–6. Bibcode :1994PNAS...91.9372G . doi :10.1073/pnas.91.20.9372 PMC 44814 PMID 7937772 . ^ a b "Entrez Gene: ZBTB7B zinc finger and BTB domain containing 7B" .
Further reading
Heegaard AM, Gehron Robey P, Vogel W, et al. (1998). "Functional characterization of the human biglycan 5'-flanking DNA and binding of the transcription factor c-Krox". J. Bone Miner. Res . 12 (12): 2050–60. doi :10.1359/jbmr.1997.12.12.2050 . PMID 9421237 . S2CID 29523309 . Ghayor C, Herrouin JF, Chadjichristos C, et al. (2000). "Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration" . J. Biol. Chem . 275 (35): 27421–38. doi :10.1074/jbc.M002139200 PMID 10856292 . Widom RL, Lee JY, Joseph C, et al. (2002). "The hcKrox gene family regulates multiple extracellular matrix genes". Matrix Biol . 20 (7): 451–62. doi :10.1016/S0945-053X(01)00167-6 . PMID 11691585 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1" . Nature . 441 (7091): 315–21. Bibcode :2006Natur.441..315G . doi :10.1038/nature04727 PMID 16710414 . Kypriotou M, Beauchef G, Chadjichristos C, et al. (2007). "Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors" . J. Biol. Chem . 282 (44): 32000–14. doi :10.1074/jbc.M705197200 PMID 17698844 .
External links
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH )
Group A Group B Group CPAS Group D Group E Group F
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors
