Wolf River may refer to:

• Wolf River (Alberta), a tributary of the Sand River
• Wolf River (British Columbia), on Vancouver Island, British Columbia
• Wolf River (Manitoba), a tributary of the Hayes River in northern Manitoba
• Wolf River (Nunavut), on Axel Heiberg Island
• Ontario
  • Wolf River (Parry Sound District), a tributary of the Pickerel River
  • Wolf River (Sudbury District), a tributary of the Wolseley River
  • Wolf River (Thunder Bay District), a tributary of Lake Superior
• Wolf River (Yukon), a tributary of the Nisutlin River

• Wolff River, in Fiordland

• Wolf River (Kansas) in Kansas
• Wolf River (Mississippi) in southern Mississippi, which empties into Bay St. Louis
• Tennessee
  • Wolf River (Tennessee), in western Tennessee
    • Wolf River Conservancy, advocates of the river
  • Wolf River (Middle Tennessee), in middle Tennessee
• Wisconsin
  • Wolf River (Fox River tributary), a Fox River tributary
  • Wolf River (Eau Claire River), a North Fork Eau Claire River tributary

• Wolf River, Langlade County, Wisconsin, United States
• Wolf River, Winnebago County, Wisconsin, United States

• Wolf River (apple), an apple cultivar

• River Wolf, a river in Devon, England
• River Wolf (disambiguation)