Thomas Randolph may refer to:

• Thomas Randolph (ambassador) (1523–1590), English diplomat and politician
• Thomas Randolph (poet) (1605–1635), English poet and dramatist
• Thomas Randolph of Tuckahoe (1683–1729), Virginia politician
• Thomas Randolph (academic) (1701–1783), Vice-Chancellor of Oxford University
• Thomas Randolph, 1st Earl of Moray (died 1332), nephew and companion-in-arms of King Robert the Bruce
• Thomas Randolph, 2nd Earl of Moray (died 1332), son of the 1st Earl of Moray
• Thomas Mann Randolph Jr. (1768–1828), Representative from Virginia
• Thomas Jefferson Randolph (1792–1875), served in the Virginia House of Delegates
• Thomas Randolph (American football) (born 1970), American football player
• Thomas Randolph (priest) (1904–1987), Archdeacon of Hereford
• Thomas Beverly Randolph (1793–1867), American military officer
• Thomas Mann Randolph Sr. (1741–1793), politician in Virginia