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The number of cases of infection with the Omicron variant has increased again in Romania, according to the health authorities. Another 9 new cases were registered on Thursday, bringing the total number of cases in Romania to 25, reports the Ministry of Health. 109.101.119.76 (talk) 17:43, 23 December 2021 (UTC)[reply]

https://www.digi24.ro/amphtml/stiri/actualitate/au-fost-descoperite-inca-9-cazuri-de-infectare-cu-varianta-omicron-in-romania-1779323 — Preceding unsigned comment added by 109.101.119.76 (talk) 17:44, 23 December 2021 (UTC)[reply]

 Done Romania updated to 25 cases. crannofonix (talk) 09:39, 24 December 2021 (UTC)[reply]

Macedonia has confirmed it's first case of the Omicron variant today. 141.136.15.156 (talk) 19:55, 24 December 2021 (UTC)[reply]

 Done Added Macedonia. Thank you for making Wikipedia a better place!Crannofonix (talk) 08:54, 26 December 2021 (UTC)[reply]

https://www.reuters.com/world/europe/kosovo-reports-first-cases-covid-19-omicron-2021-12-26/ — Preceding unsigned comment added by 86.115.89.96 (talk) 21:55, 26 December 2021 (UTC)[reply]

 Partly done. Kosovo has been added to the statistics table with 9 cases in Column 4 (for other sources). Someone else will need to add Kosovo to the map. SpookiePuppy (talk) 13:28, 28 December 2021 (UTC)[reply]

On 10 December 2021, the UK Health Security Agency reported that early data indicated a 20- to 40-fold reduction in neutralizing activity for Omicron by sera from Pfizer 2-dose vaccinees relative to earlier strains and a 20-fold reduction relative to Delta. The reduction was greater in sera from AstraZeneca 2-dose vaccinees, falling below the detectable threshold. An mRNA booster dose produced a similar increase in neutralising activity regardless of the vaccine used for primary vaccination. After a booster dose (usually with an mRNA vaccine),[74] vaccine effectiveness against symptomatic disease was at 70%–75%, and the effectiveness against severe disease was expected to be higher.[75]

***vvvvvvvvvvvv*** seems it should be december?

On 26 November 2021 the WHO asked nations to do the following:

Enhance surveillance and sequencing efforts to better understand circulating SARS-CoV-2 variants. Submit complete genome sequences and associated metadata to a publicly available database, such as GISAID. Report initial cases/clusters associated with virus-of-concern infection to WHO through the IHR mechanism. Where capacity exists and in coordination with the international community, perform field investigations and laboratory assessments to improve understanding of the potential impacts of the virus of concern on COVID-19 epidemiology, severity, and the effectiveness of public health and social measures, diagnostic methods, immune responses, antibody neutralization, or other relevant characteristics.[76] 174.91.198.71 (talk) 01:20, 27 December 2021 (UTC)[reply]

 Not done: it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a reliable source if appropriate. --Hemanthah (talk) 03:44, 28 December 2021 (UTC)[reply]

Under the subsection Mutations, there's a sentence that states "...it is believed that one of these many mutations, comprising a 9-nucleotide sequence, may have been acquired from another type of virus (known as HCoV-229E), responsible for the common cold." I believe this statement could be strengthened by specifying exactly what the insertion mutation is, i.e. ins214EPE. I think at one point this article did state which mutation it was but has since been removed due to some dubious claims and confusion over the interpretation of a pre-print^[1]. It is clear that this insertion mutation (ins214EPE) has not appeared in any SARS-CoV-2 variant or sublineage other than Omicron. It also seems more likely than not that the insertion mutation is eventually going to be confirmed (in a peer-reviewed publication) as being the same one that is found in HCoV-229E (although it seems the position is just out-of-frame with HCoV-229E). The pre-print titled "Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin" seems to be suggesting the possibility of co-infection: "Thus, the evolution of the unique insertion in Omicron could have been based on template switching during viral co-infections, or from prevalent templates in the human genome" and also co-expression of entry receptors (ACE2 and ANPEP). I realise that there are community sanctions in place over the use of pre-prints in certain COVID-19-related articles, so we will need to wait until more research has been published, but if there is someone who can help sort this out, it would be great. SpookiePuppy (talk) 16:21, 28 December 2021 (UTC)[reply]

Bryant, Nadeem Badshah (now); Miranda; Bryant, Tom; Farrer, Martin; Cassidy (earlier), Caitlin; Ahmed, Kaamil; McKie, Robin; Savage, Michael (December 26, 2021). "Covid live: US reports highest seven-day cases average since January; UK 'considering door-to-door vaccinations'" – via www.theguardian.com.

seems to mention more cases - this source is in the timeline of omicron article where it also says 115 different places - yet we have 108 in this article - where is the discrepancy? — Preceding unsigned comment added by 86.115.73.249 (talk) 22:46, 28 December 2021 (UTC)[reply]

I am sure many more cases in existence in many places. BUT here is an article

https://yle.fi/uutiset/3-12249910

with a higher finland figure: i.e 172 in Just Hesinki area

"New studies tell of the disease of omicron And then to omikron: promising good and bad news.

According to Salminen, a study in Scotland says that the disease caused by omicron appears to be 40 to 60 percent less delta, according to preliminary results. This has been assessed in the past, but new and high-quality studies seem to support the finding.

Omikron is displacing the delta throughout Europe, and has already displaced it regionally. There are no special risk countries anymore, as in Finland, too, omikron seems to have become mainstream in the HUS area.

Based on screening tests, Omikron already accounts for 70 percent of new cases in the HUS area. So far, 172 cases have been identified."

Please replace "34" with "172" in table. — Preceding unsigned comment added by 86.115.73.249 (talk) 14:10, 29 December 2021 (UTC)[reply]

Not done for now: Could you please provide a better source that says that there are 172 omicron cases? Thanks Crannofonix (talk) 01:20, 30 December 2021 (UTC)[reply]

Note: the UK is unfortunately no longer updating figures specifically for omicron as it is now the dominant strain affecting the UK. So the case figures cannot be filtered for just omicron anymore. See note on page 1 of https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1044522/20211231_OS_Daily_Omicron_Overview.pdf — Preceding unsigned comment added by 86.149.212.192 (talk) 01:44, 2 January 2022 (UTC)[reply]

Yes, thanks for pointing this out. The note you are referring to states: "As VOC Omicron is now the dominant strain within England, with effect from 1 January 2022 UKHSA will no longer be separately reporting VOC Omicron statistics. Daily COVID-19 statistics continue to be available via UK Summary Coronavirus (COVID-19) in the UK (data.gov.uk)"[1] And: [2]. SpookiePuppy (talk) 18:51, 3 January 2022 (UTC)[reply]

When/if secondary sources are found, is this something worth mentioning? According to a peer-reviewed study accepted for publication in the Journal of Genetics and Genomics, "results suggest that the progenitor of Omicron jumped from humans to mice, rapidly accumulated mutations conducive to infecting that host, then jumped back into humans". https://www.sciencedirect.com/science/article/pii/S1673852721003738 --Xarm Endris (talk) 08:57, 3 January 2022 (UTC)[reply]

Would require WP:MEDRS sourcing; this is primary research. Alexbrn (talk) 09:02, 3 January 2022 (UTC)[reply]

Is this publication itself not a peer response to the hypothesis that the variant originated in “an immunocompromised individual who provided a suitable host environment conducive to long-term intra-host virus adaptation”? In that context the article can be cited.— Frdp (talk) 18:08, 3 January 2022 (UTC)[reply]

https://sofiaglobe.com/2022/01/02/covid-19-in-bulgaria-omicron-variant-found-in-12-samples-sequenced-by-ncipd/ gives a source for case numbers - marked on the map, but not in the table.