Schultze is a German surname. Notable people with the surname include:

• Bernhard Sigmund Schultze (1827–1919), German gynecologist
• Charles Schultze (1924–2016), U.S. economist
• Ernst Schulze (disambiguation) several people including:

• Ernst Schulze (poet), a German Romantic poet
• Gottlob Ernst Schulze, a German philosopher
• Ernst Schulze (chemist), a German Chemist and the grandson of Gottlob Ernst Schulze
• Sadananda, born Ernst-Georg Schulze, a German Gaudiya Vaishnavist swami

• Fritz Schultze (1846–1908), German philosopher
• Gottlob Ernst Schulze (1761–January 1833), German philosopher, grandfather of biochemist Ernst Schulze
• Hans-Peter Schultze (born 1937), German-American paleoichthyologist
• Max Schultze (1825–1874), German microscopic anatomist
• Norbert Schultze (1911–2002), German composer of film music
• Rainer Schultze-Kraft (1941-2024), German agronomist specialized in tropical agriculture
• Sven Schultze (born 1978), German basketball player

• Schultze Gets the Blues, a 2003 film directed and written by Michael Schorr
• All pages with titles containing Schultze