Robert Blake (or variants) may refer to:

• Bob Blake (American football) (1885–1962), American football player
• Robbie Blake (born 1976), English footballer
• Bob Blake (ice hockey) (1914–2008), American ice hockey player
• Rob Blake (born 1969), Canadian ice hockey player

• Robert O. Blake (1921–2015), American diplomat
• Robert O. Blake Jr. (born 1957), American diplomat, son of above

• Robert Blake (admiral) (1598–1657), English admiral
• Robert Blake (Medal of Honor), American Civil War sailor, first African-American to receive the Medal of Honor
• Robert Blake (USMC) (1894–1983), United States Marine Corps general

• Robert Blake (actor) (1933–2023), American actor, starred in the TV series Baretta
• Robert Blake (folk singer) (fl. 21st century), American folk singer
• Bobby Blake (born 1957), American pornographic actor turned Baptist elder

• Robert Blake (cabinetmaker) (fl. 1826–1839), London cabinetmaker
• Robert Blake (dentist) (1772–1822), Irish dentist
• Robert Blake, Baron Blake (1916–2003), English historian
• Robert Pierpont Blake (1886–1950), American Byzantist and Orientalist
• Robert R. Blake (1918–2004), American management theoretician, developer of the Managerial Grid Model
• Robert Blake, brother of poet William Blake (1757–1827), who William claimed visited him in his dreams

• Robert Blake (detective), a fictional detective character created by novelist Dinendra Kumar Roy
• Bob Blake, in a series of African-American westerns from the 1930s played by Herb Jeffries
• Robert Blake, from Bungie' computer game Marathon 2: Durandal
• Robert Harrison Blake, from H. P. Lovecraft's short story "The Haunter of the Dark"

• Blake (disambiguation)