Picún Leufú
Department
Country	Argentina
Province	Neuquén
Capital	Picún Leufú
Area
• Total	4,580 km2 (1,770 sq mi)
Population  (2022)
• Total	5,087[1]
Important cities	Picún Leufú El Sauce Limay Centro Paso Aguerre Aguada del Carrizo

Picún Leufú is a department located in the east of Neuquén Province, Argentina.

The Department limits with Confluencia Department at northeast, Rio Negro Province at southeast, Collón Curá Department at southwest, Catán Lil Department at west and Zapala Department at northwest.

39°31′07″S 69°17′28″W / 39.51861°S 69.29111°W / -39.51861; -69.29111